May 21 continues the intense gaming marathon on the League of Legends scene. We've selected five matches with the best combination of statistics, team form, and odds — sharing predictions for the day, covering Circuito Desafiante 2025 Split 1, LCK 2025 Season, and LPL Split 2 2025.

Los Grandes to defeat Keyd Stars Academy (odds 1.72)

In the upper bracket semifinals of Circuito Desafiante 2025, Los Grandes will face the academy team Keyd Stars Academy. Despite the LAN format, Los Grandes appear more confident: consistent performances in the regular season and an aggressive play style make them the favorite. A victory for LG (1.72) is a bet on experience and team synergy.

Gen.G to defeat Hanwha Life Esports (odds 1.42)

The opening series for Gen.G in the new LCK season — and right against the unstable HLE. Gen.G is known for reliable lane play and smart macro. A win for Gen.G (1.42) is a bet on class and discipline.

Anyone's Legend to defeat JD Gaming (odds 1.62)

The match within LPL Split 2 looks intriguing: AL is in good form and shows progress in coordination. JD Gaming has yet to find the optimal lineup and struggles in the mid-game. A victory for AL (1.62) is a bet on momentum and current form.

DRX to defeat DN Freecs (odds 1.65)

DRX has strengthened during the off-season and demonstrates confident pressure through the side lanes. Freecs has yet to show a clear strategy. A win for DRX (1.65) is a bet on draft depth and tempo play.

Bilibili Gaming to defeat Invictus Gaming (odds 1.40)

BLG enters the split with ambitions and a strong roster. IG, on the other hand, is seeking stability and rarely maintains initiative after the laning phase. A victory for BLG (1.40) is a bet on a confident start to the split.

Spring in LoL is full of surprises, but analysis and calculation always remain valuable. Bet wisely and remember: the strongest team is the one that can adapt.

Odds provided by Stake and are current at the time of publication.